"Give Me One Reason" is Chapman's biggest US hit to date, reaching #3 on the US Hot 100. Chapman earned the Grammy Award for Best Rock Song for the track, that was also nominated for Record of the Year, Song of the Year and Female Rock Vocal Performance at the Grammy Awards of 1997. The album New Beginning got to #4 on Billboard's 200 Album chart, and this song's single went platinum.
Chapman in fact makes a career out of '60s-style folk-blues rock, making her territory "folk revival," complete with the social and political message that also defined the Flower Power generation. "Give Me One Reason," then, is a straightforward blues love song, with a defiant slant daring you to argue with her to get her to stay.