"Call Me" was number one for six consecutive weeks on the Billboard Hot 100 chart, where it became the band's biggest single and second #1. In the year-end charts of 1980 it was Billboard's #1 hit, and according to Billboard magazine, was the top-selling single of the year in the United States in 1980.
"Call Me" was the main theme song of the 1980 film American Gigolo. The lyrics were written from the perspective of the main character in the film, a male prostitute.