"Ain't No Stoppin' Us Now" proved to be a successful crossover hit, peaking at number 13 on the Billboard Hot 100 and reached number 5 in the UK. The single also made it to number 10 on the disco charts. It eventually went double platinum, selling over 2 million copies.
John Whitehead claimed that he made up the lyrics on the spot in the studio, and did his vocal in just one take. Wayman Tisdale recorded an instrumental version for his 2004 album Hang Time that was a hit on American smooth jazz radio stations.
